Trisenox(arsenic trioxide)
Arsenic Trioxide, Trisenox (arsenic trioxide) is a small molecule pharmaceutical. Arsenic trioxide was first approved as Trisenox on 2000-09-25. It is used to treat promyelocytic leukemia acute in the USA. It has been approved in Europe to treat promyelocytic leukemia acute.
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Commercial
Trade Name
FDA
EMA
Arsenic trioxide, Trisenox (discontinued: Arsenic trioxide, Trisenox)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| arsenic trioxide | ANDA | 2024-11-15 |
| trisenox | New Drug Application | 2023-09-07 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| promyelocytic leukemia acute | — | D015473 | C92.4 |
Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
ARSENIC TRIOXIDE, TRISENOX, CEPHALON | |||
| 2025-01-12 | ODE-167 | ||
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J9017 | Injection, arsenic trioxide, 1 mg |
Clinical
No data
Drug
General
| Drug common name | Arsenic trioxide |
| INN | — |
| Description | Arsenic trioxide, sold under the brand name Trisenox among others, is an inorganic compound with the formula As2O3. As an industrial chemical, its major uses include the manufacture of wood preservatives, pesticides, and glass. It is also used as a medication to treat a type of cancer known as acute promyelocytic leukemia. For this use it is given by injection into a vein.
|
| Classification | Small molecule |
| Drug class | Antineoplastic agent |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O1[As]2O[As]3O[As]1O[As](O2)O3 |
Identifiers
| PDB | — |
| CAS-ID | 1327-53-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2362016 |
| ChEBI ID | 30621 |
| PubChem CID | 261004 |
| DrugBank | DB01169 |
| UNII ID | — |
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
Black-box warning for: Arsenic trioxide, Trisenox
Adverse Events
0 adverse events reported
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